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Table 1 Detailed descriptions of included studies

From: Perioperative systemic steroid for rapid recovery in total knee and hip arthroplasty: a systematic review and meta-analysis of randomized trials

Author (Year) Surgery Size (E/C) Delivery way Dose of steroid Anesthesia Country Follow-up
Koh et al. (2013)[12] TKA 269 (135/134) IV 10 mg DA before operation and further dose at end of operation (H) SA Korea 1 year
Fujii et al. (2005) [13] TKA 80 (20/20/20/20) IV 4 mg (L) or 8 mg (H) or 16 mg (H) DA at end of operation GA or SA Japan Unclear
Jules-Elysee et al. (2011) [14] TKA 30 (15/15) IV 100 mg HC before operation and futher dose at 8 h later (L) SA USA 6 months
McLawhorn et al. (2014) [15] TKA 23 (11/12) IV 100 mg HC before operation and followed by 2 doses each 8 h apart (H) SA USA Unclear
Jules-Elysee et al. (2012) [16] TKA 34 (17/17) IV 100 mg HC before operation and further dose at 8 h later (L) SA USA 6 months
Bergeron et al. (2009) [17] THA 50 (25/25) IV 40 mg DA before operation (H) SA Canada 1 year
Lunn et al. (2011) [20] TKA 48 (24/24) IV 125 mg MP before operation (H) SA Denmark 1 month
Backes et al. (2013) [21] TKA/
THA
TKA:68 (28/25/20)
THA:47 (13/17/17)
IV E1: 10 mg DA before operation (H)
E2: 10 mg DA before operation and further dose at 24 h later (H)
GA USA 6 months at least
Sculco et al. (2015) [22] THA 27 (13/14) PO + IV 20 mg PD orally before operation, followed by 2 doses 100 mg HC intravenously each 8 h apart (H) SA USA 3 months
Lunn et al. (2013) [23] THA 48 (24/24) IV 125 mg MP before operation (H) SA Denmark 1 month
Kardash et al. (2007) [24] THA 50 (25/25) IV 40 mg DA before operation (H) SA Canada 1 month
  1. E experimental group, C control group, IV intravenous injection, PO oral administration, DA dexamethasone, HC hydrocortisone, PD prednisone, MP methylprednisolone, SA spinal anesthesia, GA general anesthesia, H high-dose steroid, dexamethasone > 0.1 mg/kg or other equivalent steroid, L low-dose steroid, dexamethasone ≤ 0.1 mg/kg or other equivalent steroid