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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: LncRNA-ANCR regulates the cell growth of osteosarcoma by interacting with EZH2 and affecting the expression of p21 and p27

Fig. 3

Downregulation of lncRNA-ANCR suppressed the expression of EZH2 and activated p21 and p27. a The downregulation of lncRNA-ANCR by siRNA interference was validated by RT-PCR. *P < 0.05. b The relative mRNA level of EZH2 in cells with the indicated treatments was measured by RT-PCR. *P < 0.05. c, d The mRNA level of p21 (c) and p27 (d) in MG-63 and UMR-106 cells expressing lncRNA-ANCR or control vector was detected. *P < 0.05. e The protein abundance of p21 and p27 in OS cells with or without lncRNA-ANCR depletion

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X