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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Effects of annulus defects and implantation of poly(lactic-co-glycolic acid) (PLGA)/fibrin gel scaffolds on nerves ingrowth in a rabbit model of annular injury disc degeneration

Fig. 6

mRNA expression of aggrecan, Col1A1, Col2A1, and MMP-3 at 6 months after surgery. There was a marked reduction of aggrecan and Col2A1 and a significant increase of Col1A1 and MMP-3 expression in the injured discs, compared with those in the control group. The mRNA expression in the PLGA/fibrin gel implantation group was comparable to that in the control group (P > 0.05). (*P < 0.01 vs. control group; # P < 0.01 vs. PLGA/fibrin gel implantation group)

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