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Table 5 Adverse events in the SOC ‘musculoskeletal and connective tissue disorders’ (safety population)

From: Safety of three different product doses in autologous chondrocyte implantation: results of a prospective, randomised, controlled trial

Dose group Low dose Medium dose High dose
N = 25 N = 25 N = 25
Relationship NR Unl Pos Pro NR Unl Pos Pro NR Unl Pos Pro
Any adverse event 3 5 6 14 3 3 7 23 6 4 7 19
Joint effusion 4 13 2 21 1 1 2 17
Arthralgia 2 2 2 1 2 1 1 3 1 3 1
Joint swelling 1 2 1 2 1 1
Joint crepitation 1 2 1 1 1
Chondropathy 1 1 2
Back pain 1 2
Tendonitis 1 1 1
Joint lock 2
Muscular weakness 1
Bone cyst 1
Bone pain 1 1
Intervertebral disc prot. 1
Ligament disorder 1
Muscle atrophy 1
Myalgia 1
Osteoarthritis 1
Patellofemoral pain sy. 1
  1. Numbers of patients are given
  2. prot. protrusion, sy. syndrome