From: A survey of proteomic biomarkers for heterotopic ossification in blood serum
Biological pathway | Pathway database | Ratio | Pathway proteins | Dataset proteins | p value | FDR |
---|---|---|---|---|---|---|
Extracellular matrix organization | R | 0.0243 | 248 | 64 | 1.11E−16 | 1.30E−14 |
ECM-receptor interaction | K | 0.0085 | 87 | 31 | 1.11E−16 | 1.30E−14 |
Response to elevated platelet cytosolic Ca2+ | R | 0.0081 | 83 | 45 | 1.11E−16 | 1.30E−14 |
Complement and coagulation cascades | K | 0.0068 | 69 | 46 | 1.11E−16 | 1.30E−14 |
Beta1 integrin cell surface interactions | N | 0.0065 | 66 | 27 | 1.11E−16 | 1.30E−14 |
Formation of fibrin clot (clotting cascade) | R | 0.0038 | 39 | 24 | 1.11E−16 | 1.30E−14 |
Focal adhesion | K | 0.0203 | 207 | 37 | 8.46E−12 | 8.46E−10 |
Staphylococcus aureus infection | K | 0.0054 | 55 | 18 | 2.67E−10 | 2.35E−08 |
Beta3 integrin cell surface interactions | N | 0.0042 | 43 | 16 | 4.32E−10 | 3.37E−08 |
L1CAM interactions | R | 0.0077 | 79 | 20 | 2.15E−09 | 1.38E−07 |