Table 3 Comparison of Mankin score, the MMP-13 and TIMP-1 expression level in the medial tibial plateau at all the time points between the PCL rupture groups and the control groups in the PCL rupture rabbit model (Wilcoxon rank-sum test)
4th week | 8th week | 16th week | 24th week | ||
|---|---|---|---|---|---|
Mankin score | PCL rupture group | 0.58 ± 0.67 | 5.67 ± 0.89 | 8.33 ± 0.89 | 11.00 ± 1.28 |
Control group | 0.42 ± 0.52 | 0.42 ± 0.67 | 0.50 ± 0.67 | 0.58 ± 0.67 | |
P value | >0.05 | <0.05 | <0.05 | <0.05 | |
MMP-13 | 12.95 ± 1.55 | 50.95 ± 4.30 | 43.87 ± 4.14 | 17.02 ± 0.90 | 12.95 ± 1.55 |
4.11 ± 2.59 | 4.70 ± 3.36 | 4.46 ± 3.00 | 4.77 ± 2.37 | 4.11 ± 2.59 | |
P value | <0.05 | <0.05 | <0.05 | <0.05 | |
TIMP-1 | PCL rupture group | 10.03 ± 0.89 | 31.86 ± 3.77 | 29.85 ± 3.57 | 5.99 ± 0.98 |
Control group | 4.95 ± 3.26 | 5.55 ± 3.82 | 5.13 ± 3.56 | 4.67 ± 2.90 | |
P value | <0.05 | <0.05 | <0.05 | >0.05 |