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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions

Fig. 3

Morphological change in the motor neuron following ischemia–reperfusion injury with or without simvastatin. a Without simvastatin. Ischemia–reperfusion damage resulted in massive cell loss and destruction of neural networks. b With simvastatin. Treatment of simvastatin markedly increased neuronal survival after ischemia–reperfusion damage. Cells treated with simvastatin showed preserved morphological features of neurons with a denser meshwork of neurites when compared to (a)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X