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Table 3 Overview of patients without success

From: Effect of a standardized treatment regime for infection after osteosynthesis

Patient no.

Follow-up (mo)

Fracture, Gustilo

Closure

MB

Rifampicin resistance

Treatment

Failure reason

1

16

Distal tibia/fibula, IIIA

Free flap

PM

No

Multiple surgical debridement, local antibiotic treatment, revision osteosynthesis, 2× protocol treatment

Amputation necessary

2

24

Pelvic ring, IIIC

Free flap

PM

Yes

Removal OSM at initial debridement, multiple surgical debridement, local antibiotic treatment

Non-union, continuous soft tissue problems

3

16

Distal femur, IIIC

Split skin graft

PM

No

Multiple surgical debridement and antibiotic therapy, local antibiotic therapy, removal OSM

Non-union, persisting low grade infection

4

15

Shaft tibia/fibula, IIIB

Free flap

CoNS

Yes

Masquelet technique, surgical debridement, no intravenous antibiotic therapy, when relapse adequate protocol treatment

Non-union

5

10

Distal femur, I

Primary

NG

NA

Infection after re-osteosynthesis for pseudo-arthrosis, single surgical debridement, perfect protocol treatment

Non-union

6

11

Shaft tibia/fibula, unknown

Split skin graft

PM

No

Infection after sequestrectomy and re-osteosynthesis for pseudo-arthrosis, multiple surgical debridement and antibiotic treatment.

Non-union, persisting wound

  1. mo months, MB microbiology, PM polymicrobial, CoNS coagulase-negative Staphylococci, NG no growth, OSM osteosynthetic material, NA not applicable