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Table 2 Infection and treatment characteristics and association with primary cure

From: Effect of a standardized treatment regime for infection after osteosynthesis

Variable

Baseline

Primary success rate

P value

(n = 49)

No (n = 18)

Yes (n = 31)

Infection

 Type of infection

   

0.260

  Early

44

15

29

 

  Delayed

5

3

2

 Microorganism

    

  Negative culture

5

1

4

0.623

   Staphylococcus aureus

16

6

10

1.0

  CoNS

2

1

1

1.0

  Polymicrobial culture

21

10

11

0.206

  Other single microorganism

4

4

0.282

 Rifampicin resistance at first culture

3

2

1

0.544

 Rifampicin resistance in all cultures

8

5

3

0.250

Treatment

 Number of debridements performed

2 (0–14)

3 (0–14)

2 (1–5)

0.015

 Closure

  Primary closure

23

4

19

0.017

  VAC therapy after debridement

17

10

7

0.030

  Time to closure after debridement, days

157 (8–700)

271 (38–700)

149 (8–157)

0.000

 Antibiotic therapy

  Duration i.v. antibiotic therapy

10 (0–116)

14 (0–77)

10 (0–116)

0.203

  Duration oral antibiotic therapy

70 (0–112)

63 (0–89)

70 (0–112)

0.033

  Duration total antibiotic therapy

80 (0–126)

80 (0–126)

81 (9–116)

0.186

  Duration of rifampicin therapy

80 (5–116)

75 (6–97)

80 (5–116)

0.118

 NSAID use during treatment

36

14

31

0.743

 Treated according to protocol

   

0.025

  Yes

39

11

28

 

  No

10

7

3

 
  1. Data are presented as the number of cases with the percentage in parenthesis or as median with the range in parenthesis
  2. i.v. intravenous
  3. P values of <0.05 are considered significant. Only P values of <0.05 are in italic