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Table 9 Table showing the types of scaffold used in animal studies

From: The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review

Scaffold type

No. of studies

References

No Scaffold

19 (17%)

[49, 54, 61, 70, 72–75, 81, 86, 89–91, 97, 100, 102, 280–282, 284]

Poly (lactide-co-glycoside) PLGA

17 (16%)

[56, 59, 62, 63, 83, 88, 150, 153, 160, 277, 285, 286, 289–292, 316]

Fibrin/Fribrin glue

11 (9%)

[55, 64, 76–78, 152, 278, 293, 308, 317, 318]

Hydrogel

9 (8%)

[65, 69, 81, 94, 279, 288, 314, 321, 323]

Collagen

9 (8%)

[79, 80, 134, 276, 299, 301, 309, 320, 322]

Hyaluronic acid

7 (6%)

[57, 92, 95, 96, 273, 304, 324]

Alginate beads

4 (3%)

[65, 84, 101, 294]

Tissue membrane

4 (3%)

[82, 98, 303, 305]

Polyglycolic acid

3 (3%)

[99, 161, 274]

PGA/PLA

3 (3%)

[68, 290, 296]

Hylauronan crosslinked matrix

2 (2%)

[154, 297]

Poly-L-lactide-co-caprolactone

2 (2%)

[275, 300]

Polycaprolactone cartilage (PCL)

2 (2%)

[87, 272]

Animal-origin osteochondral plug scaffold

2 (2%)

[272, 298]

Chitosan microspheres and fibrin glue

1 (<1%)

[60]

Gel carries (collagen/HA/Fibrogen)

1 (<1%)

[71]

Polychoxanone/poly(vinyl alcholo) PDO/PVA

1 (<1%)

[302]

Cartilage aggregate

1 (<1%)

[306]

Collagen/glycosaminoglycan porous titanium biphasic scaffold

1 (<1%)

[151]

Articular chondrocyte seeded matrix associated autologous chondrocyte transplant (MACT)

1 (<1%)

[313]

MSC-ADM (accellulo-dermal matrix)

1 (<1%)

[319]

Hyaff-11 scaffold

1 (<1%)

[295]

Porous-gelatin-chonroitin hyaluronate

1 (<1%)

[291]

Bone protein 7 PCL

1 (<1%)

[66]

Human acellular amniotic membrane

1 (<1%)

[307]

Pluronic-F 127

1 (<1%)

[102]

Tricalcium phosphate

1 (<1%)

[315]

Agarose

1 (<1%)

[311]

GCH-GCBB

1 (<1%)

[93]

ACHMS (atelocollagen honeycomb-shaped membrane)

1 (<1%)

[58]

Magnet

1 (<1%)

[310]

Human cartilage extra cellular matrix 3D porous acellular

1 (<1%)

[67]