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Table 1 Characteristics of included studies

From: Comparison of the effectiveness and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials

Authors

Patients (T/I)

Age (mean year) (C/I)

Gender (F/M)

Diagnosis

Country

Type of prosthesis

Surgical protocol

Pneumatic tourniquet

Follow-up

Patel JN 2014 [31]

47/42

42/64.9

23/66

OA

USA

ns

Con-TKA

Yes

4.6

Maniar RN 2012 [30]

40/160

67.4/67.45

42/158

OA

India

Cemented

CAS-TKA

Yes

3

Seo JG 2013 [33]

50/50

67.5/66.8

11/89

OA

Korea

Cemented

CAS-TKA

Yes

2

Sarzaeem MM 2014 [32]

100/50

67.8/66.9

20/130

OA

Iran

Cemented

Con-TKA

Yes

–

Soni A 2014 [34]

40/40

69.45/69.05

36/44

OA

India

Cemented

Con-TKA

Yes

1.5

Tang Lian 2014 [29]

30/30

66.5/67.1

20/40

OA

China

ns

Con-TKA

Yes

–

Han WF 2014 [26]

50/50

ns

20/80

OA + RA

China

Cemented

Con-TKA

Yes

3 months

Aguilera X 2015 [24]

50/50

72.53/72.49

70/30

OA + RA + DKD

Spain

Cemented

Con-TKA

Yes

2

Digas G 2015 [25]

30/30

70/71

51/49

OA

Germany

Cemented

Con-TKA

Yes

25 days

Jiang Hua 2015 [28]

33/40

ns

54/19

DKD

China

ns

Con-TKA

Yes

7 days

Hou ZY 2015 [36]

20/20

67.36/67.02

 

OA + RA

China

Uncemented

Con-TKA

Yes

14 days

  1. NS not stated, T topical group, I intravenous group, OA osteoarthritis, RA rheumatoid arthritis, DKD degenerative knee disorders, Con-TKA conventional total knee arthroplasty, CAS-TKA computer-assisted total knee arthroplasty