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Table 3 Functional enrichment analysis for the 16 differentially expressed genes in the three significant modules

From: Screening for potential genes associated with bone overgrowth after mid-shaft femur fracture in a rat model

GO-ID P value corr P value x Description
Module A
 19934 1.47E−06 8.16E−04 2 cGMP-mediated signaling
 6916 7.95E−06 2.21E−03 3 Anti-apoptosis
 48856 6.61E−05 8.68E−03 5 Anatomical structure development
 43066 1.13E−04 8.68E−03 3 Negative regulation of apoptosis
 43069 1.17E−04 8.68E−03 3 Negative regulation of programmed cell death
 1936 1.19E−04 8.68E−03 2 Regulation of endothelial cell proliferation
 51239 1.26E−04 8.68E−03 4 Regulation of multicellular organismal process
 60548 1.31E−04 8.68E−03 3 Negative regulation of cell death
 10646 1.49E−04 8.68E−03 4 Regulation of cell communication
 32502 1.56E−04 8.68E−03 5 Developmental process
Module B
 6811 2.28E−07 1.94E−05 5 Ion transport
 6813 2.82E−06 1.20E−04 3 Potassium ion transport
 55085 9.85E−06 2.79E−04 4 Transmembrane transport
 15672 4.56E−05 9.69E−04 3 Monovalent inorganic cation transport
 51899 6.14E−05 1.01E−03 2 Membrane depolarization
 6810 7.76E−05 1.01E−03 5 Transport
 51234 8.34E−05 1.01E−03 5 Establishment of localization
 30001 1.42E−04 1.50E−03 3 Metal ion transport
 51179 1.67E−04 1.58E−03 5 Localization
 6812 2.86E−04 2.43E−03 3 Cation transport
Module C
 35023 3.21E−08 7.84E−06 4 Regulation of Rho protein signal transduction
 46578 6.27E−07 5.06E−05 4 Regulation of Ras protein signal transduction
 6917 8.14E−07 5.06E−05 4 Induction of apoptosis
 12502 8.29E−07 5.06E−05 4 Induction of programmed cell death
 51056 1.58E−06 7.73E−05 4 Regulation of small GTPase-mediated signal transduction
 8624 2.74E−06 1.12E−04 3 Induction of apoptosis by extracellular signals
 43065 6.29E−06 1.59E−04 4 Positive regulation of apoptosis
 43068 6.50E−06 1.59E−04 4 Positive regulation of programmed cell death
 6915 6.64E−06 1.59E−04 4 Apoptosis
 10942 7.15E−06 1.59E−04 4 Positive regulation of cell death