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Table 1 Characteristics of the included studies

From: A meta-analysis of randomized control trials of surgical methods with osteosarcoma outcomes

Ref. Study period Patient number Male/female Median age (range) Enneking stage Country
Ferrari et al. 1983–1986 127 (91/35) 72/55 15 (5–43) Stage IIB Austria
Bacci et al. 1986–1993 29 (25/4) 20/9 46 Stage IIB Italy
Edmonson et al. 1976–1980 38 (1/37) 24/14 17 (9–62) Stage IIB Austria
Gherlinzoni et al. 1983–1988 355 (239/116) Stage IIA Italy
Goorin et al. 1976–1989 74 (36/38) Stage IIA Austria
Zhang et al. 1981–1997 31 (17/14) 26/5 15 (7–42) Stage IIB China
Sha et al. 1989–2006 56 (35/21) 18 (2–46) Stage IIA China
Niu et al. 1992–2001 189 (140/49) 125/64 18 (4–39) Stage IIB China
Bramer et al. 1983–2003 56 (44/12) 36/20 16 (3–36) Stage IIB America
Ferguson et al. 1989–2006 31 (19/12) 14/17 30 (11–32) Stage IIB America