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Table 1 Characteristic of the included studies

From: Comparison of unilateral and bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review and meta-analysis

Author Year of publication Year of onset Mean age Sample size (unilateral/bilateral) Sex distribution (male/female) Outcome measurements Follow-up time
Chen CM [25] 2014 Unilateral group, 69.43 ± 6.25; bilateral group, 68.66 ± 8.76 39 (20/19) –/– VAS, ODI, surgery time, Cement leakage, injected cement volume 2 years
Feng Y [26] 2014 February 2010 to February 2012 Unilateral group, 72.5; bilateral group, 69.4 117 (61/56) 30/87 VAS, ODI, injected cement volume 2 years
Guo ZP [27] 2015 March 2008 to March 2014 Unilateral group, 67.32 ± 11.24; bilateral group, 69.35 ± 12.46 153 (91/62) 29/124 VAS, ODI, surgery time, Injected cement volume, cement leakage
Li J [28] 2015 April 2007 to February 2014 Unilateral group, 67.9; bilateral group, 65.7 65 (36/29) 30/35 VAS, surgery time, injected cement volume, cement leakage 6 to 18 months
Ren HL [29] 2014 January 2009 to January 2012 Unilateral group, 69.4 ± 10.4; bilateral group, 69.7±9.7 101 (45/56) 17/84 Surgery time, injected cement volume, cement leakage More than 1 year
Wang W [30] 2013 February 2009 to February 2011 Unilateral group, 66.9; bilateral group, 68.7 47 (25/22) 18/29 VAS, cement leakage 1 year
Xiao L [31] 2015 September 2012 to December 2014 Unilateral group, 70.9 ± 9.3; bilateral group, 68.5±7.3 71 (40/31) –/– VAS, injected cement volume, cement leakage 3 days
Yuan WQ [32] 2014 June 2013 to June 2014 70.36 ± 0.35 72 (36/36) 33/39 Surgery time, injected cement volume 2 days
Zhai HL
[33]
2013 January 2010 to February 2012 Unilateral group, 70.5; bilateral group, 74.3 48 (27/21) 6/42 VAS, surgery time, injected cement volume 1 day
Zhang L [34] 2015 November 2010 to October 2012 Unilateral group, 71.7 ± 7.5; bilateral group, 72.1 ± 6.0 50 (24/26) 13/37 VAS, ODI, PCS, MCS, surgery time, cement leakage, injected cement volume 2 years
Zhang LG [35] 2015 January 2008 to December 2011 Unilateral group, 70.0 ± 2.9; bilateral group, 70.7 ± 2.5 68 (36/32) 0/68 VAS, QUALEFFO, cement, cement leakage 1 year
Zhang X [36] 2014 March 2012 to August 2013 70 ± 0.27 53 (28/25) 25/28 Surgery time, injected cement volume
Zhao XQ [37] 2014 May 2011 to February 2013 Unilateral group, 74; bilateral group, 73 80 (40/40) 48/32 Curative effect, surgery time, injected cement volume 2 days
Zhou R [38] 2015 February 2011 to January 2013 Unilateral group, 68.8 ± 5.1; bilateral group, 70.6 ± 4.8 79 (41/38) 46/33 VAS, surgery time, injected cement volume, cement leakage 1 year