Fig. 2

The representative micro-CT images of the fourth lumbar vertebrae in two groups. The two-dimensional coronal images (a, b) show that the CSD group (a) has increased disconnections and separation among trabecular bone network and reduced trabecular bone connection in the central region and under the endplate region compared to the CON group (b). The three-dimensional images of the trabecular bone microarchitecture (c, d) show that the CSD group (c) has thinner trabecular bone, reduced trabecular bone connection, and more irregular trabecular bone connection. And the CSD group (c) has increased disconnections and separation among the trabecular bone network compared to the CON group (d). CSD chronic sleep deprivation, CON control