Table 1 Function enrichment analysis of DEGs
From: Identification of candidate genes for myeloma-induced osteocyte death based on microarray data
Category | GO ID | GO term | Gene count | P value |
|---|---|---|---|---|
Down | GO:0072358 | Cardiovascular system development | 35 | 2.22E-15 |
Down | GO:0072359 | Circulatory system development | 35 | 2.22E-15 |
Down | GO:0048731 | System development | 73 | 1.24E-14 |
Down | GO:0009653 | Anatomical structure morphogenesis | 55 | 1.44E-14 |
Down | GO:0031012 | Extracellular matrix | 19 | 5.70E-09 |
Down | GO:0005583 | Fibrillar collagen | 5 | 3.72E-08 |
Down | GO:0044420 | Extracellular matrix part | 12 | 5.72E-08 |
Down | GO:0005201 | Extracellular matrix structural constituent | 9 | 2.38E-08 |
Down | GO:0005178 | Integrin binding | 8 | 5.43E-07 |
Down | GO:0005198 | Structural molecule activity | 18 | 5.64E-06 |
UP | GO:0048583 | Regulation of response to stimulus | 67 | 5.57E-11 |
UP | GO:0023051 | Regulation of signaling | 59 | 2.48E-10 |
UP | GO:0010646 | Regulation of cell communication | 59 | 2.71E-10 |
UP | GO:0023052 | Signaling | 97 | 2.82E-10 |
UP | GO:0005615 | Extracellular space | 20 | 1.72E-03 |
UP | GO:0044421 | Extracellular region part | 24 | 2.83E-03 |
UP | GO:0031095 | Platelet dense tubular network membrane | 2 | 4.40E-03 |
UP | GO:0043565 | Sequence-specific DNA binding | 21 | 5.35E-05 |
UP | GO:0000982 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity | 7 | 1.95E-04 |
UP | GO:0003700 | Sequence-specific DNA binding transcription factor activity | 25 | 3.44E-04 |