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Table 2 Analysis of association of the six SNPs gene polymorphism with the risk of KBD

From: Investigation of MMP-1 genetic polymorphisms and protein expression and their effects on the risk of Kashin-Beck disease in the northwest Chinese Han population

SNPs

Genotype (%)a

Recessive model

Dominant model

KBD (N = 274)

Controls (N = 248)

P values

OR (95 % CI)

OR (95 % CI)

rs2071231

60.6/35.8/3.6

68.1/28.6/3.3

0.19

1.17 (0.43–3.18)

1.40 (0.97–2.02)

rs7125062

73.0/23.7/3.3

71.4/25.8/2.8

0.73

1.36 (0.48–3.87)

0.93 (0.63–1.37)

rs470221

47.8/37.9/14.3

47.6/45.2/7.2

0.02

2.12 (1.18–3.82)

0.99 (0.70–1.40)

rs470558

66.8/30.3/2.9

70.6/26.2/3.2

0.58

0.80 (0.30–2.10)

1.17 (0.87–1.69)

rs470206

60.2/36.5/3.3

63.3/32.7/4.0

0.46

0.65 (0.26–1.65)

1.12 (0.87–1.59)

rs1144396

47.0/37.8/15.2

46.4/45.2/8.4

0.04

1.96 (1.11–3.38)

0.96 (0.68–1.36)

  1. aHomozygote of the major allele/heterozygote/homozygote of the minor allele