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Fig. 7 | Journal of Orthopaedic Surgery and Research

Fig. 7

From: Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis

Fig. 7

The expression levels of cleaved-PARP, Bax, and Bcl-2 in fibroblasts after treatment with different concentrations of RAPA (0.01 μg/ml, 0.1 μg/ml, and 1 μg/ml) for 48 h. When the dose of RAPA increased, the levels of the pro-apoptotic proteins cleaved-PARP and Bax increased; however, the levels of the anti-apoptotic protein Bcl-2 decreased

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