From: Cross-linked versus conventional polyethylene for total knee arthroplasty: a meta-analysis
Study | Study design | Group | Simple size | Age (year) | Gender (M/F) | BMI | Manufacture | Devices information | Follow-up | Lost follow-up |
---|---|---|---|---|---|---|---|---|---|---|
Hodrick et al. 2008 [3] | CCT | XLPE | 100 | 67 ± 12 | 42/58 | NS | Compression-molded polyethylene sterilized with ethylene oxide gas preheated at 125°m and irradiated with a dose 9.5 Mrad (95 kGy) through an electron beam. | Natural knee II system (Zimmer) | Mean 75 months | 18 |
CP | 100 | 70 ± 12 | 40/60 | NS | Compression-molded polyethylene, which was gamma-irradiated in nitrogen. | Mean 82 months | 17 | |||
Minoda et al. 2009 [21] | CCT | XLPE | 89 | 70.3 ± 8.9 | 19/70 | NS | GUR 1050 UHMWPE bar cross-linked by subjection of 65 kGy of electron beam with thermal treatment above melting point, and were sterilized by gas plasma. | NexGen CR. Zimmer) | 2 years | 0 |
CP | 113 | 71.1 ± 7.3 | 20/93 | NS | Net-shape molding of GUR 1050 resin and sterilized by gamma radiation in nitrogen at a dose of 37 kGy. | 0 | ||||
Lachiewicz and Soileau 2015 [19] | RCT | XLPE | 110 | 68 ± 10 | 35/75 | 31 | Electron beam, 6.5 CGy irradiated in nitrogen, remelted to quench the free radicals; then sterilized by ethylene oxide | Zimmer, Inc, Warsaw, IN, USA | Minimum 2 years | 14 |
CP | 122 | 70 ± 10 | 37/85 | 31 | Gamma-irradiated in nitrogen | 21 | ||||
Meneghini et al. 2015 [20] | PCT | XLPE | 64 | 63.8 | 18/29 | 31.5 | GUR 1020 UHMWPE and cross-linking was performed with a cycled process of gamma-irradiation at 30 kGy followed by annealing at 130 °C for 8 h, which was repeated 3 times sequentially | Posterior-substituting single-radius design (Triathlon; Stryker, Mahwah, NJ) | 5.2 years (range, 4.3–5.8 years). | 10 |
CP | 50 | 67.3 | 12/25 | 31.1 | Compression-molded GU 1020 UHMWPE, packed in nitrogen and gamma-irradiated at 30 kGy. | 5.5 years (range, 4.8–7.4 years) | ||||
Kim and Park 2014 [17] | RCT | XLPE | 308 | 60.3 ± 4.3 | 20/288 | 29.1 | Machined from GUR1050 resin bar. | NexGen Legacy Posterior-stabilized (LPS)-Flex total knee prosthesis (Zimmer,Warsaw, Indiana) | 59 years (range, 5–6.8 years) | 0 |
CP | 308 | 60.3 ± 4.3 | 20/288 | 29.1 | Machined from GUR1050 resin bar, cross-linked by a 65-kGy electron beam | 0 | ||||
Kindsfater et al. 2015 [18] | RCT | XLPE | 477 | 66.4 ± 8.5 | 35.4 %/64.6 % | 32.6 | NS | P.F.C. Sigma fixed-bearing knees (DePuy Synthes Joint Reconstruction, Warsaw, IN). | 5-year | 298 |
CP | 449 | 66.3 ± 8.5 | 35.4 %/64.6 % | 33.2 | NS | 260 |