Fig. 2
From: Animal models of osteoarthritis: classification, update, and measurement of outcomes
Classification of osteoarthritis models based on etiology in human equivalent being studied, primary OA and post-traumatic OA. Dashed red box represents the original classification of in vivo osteoarthritis models. Blue arrows indicate the models used to replicate the disease etiology. Black arrows represent the type of models used. Both non-invasive canine and lapine models involve the use of transarticular impact. OA osteoarthritis, IATPF intra-articular tibial plateau fracture, CACTC cyclic articular cartilage tibial compression