Fig. 6
a–c Inhibition of NF-κB signaling resulted in a significant blocking of IL-1β-dependent induction in ADAMTS-4, ADAMTS-5, and aggrecan mRNA expression. Data are normalized with β-actin and are expressed as ratio to control cells. Control cell value = 1. Values are mean ± SD (n = 6 samples). *P < 0.05 vs. IL-1β alone; # P < 0.05 vs. control