Fig. 2From: IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc a, b The use of RT-PCR for the detection of ADAMTS-4, ADAMTS-5, and aggrecan mRNA expression on nucleus pulposus tissue. Values are represented as mean ± standard deviation (n = 6). P < 0.05 is considered as statistically significant. ADAMTS a disintegrin and metalloproteinase with thrombospondin motifs, Agg aggrecan, G2 grade 2 Pfirrmann, G3 grade 3 Pfirrmann, G4 grade 4 Pfirrmann, G5 grade 5 Pfirrmann. *P < 0.05 vs. controlBack to article page