Fig. 5
18F-FDG PET/CT scan images of an unsuccessfully treated animal with experimental staphylococcal tibial osteomyelitis. Sagittal images of the tibia of a rabbit demonstrating (top) increased tracer uptake (SUVmax = 3.6) with central photopenia at the area of osteomyelitis in the upper third of the tibia extending to the adjacent soft tissues (dense arrow) after 1 week of treatment and (bottom) persistent tracer activity (SUVmax = 3.8) in the tibia of the same rabbit (hollow arrow) after 3 weeks of treatment. The animal was euthanized immediately after the second 18F-FDG PET/CT scan, and both bone cultures and histology showed active infection. Note: On the left are the PET images and on the right the fused PET/CT images