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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Benefits of biphasic calcium phosphate hybrid scaffold-driven osteogenic differentiation of mesenchymal stem cells through upregulated leptin receptor expression

Fig. 3

Osteogenic protein expression. Compared to a control group, the expression of the detected osteogenic proteins in the coralline-derived-HA-group MSCs and in the BCP-group MSCs was considerably enhanced. After 14 days of culture, the protein levels of leptin-R (**p < 0.01, n = 3), leptin (0.70 ± 0.06-fold, *p < 0.05, n = 3), and Runx2 (*p < 0.05, n = 3) were significantly higher in the BCP/osteogenic-group MSCs than in the BCP/control-group MSCs. Additionally, the protein levels of leptin-R (**p < 0.01, n = 3) and Runx2 (**p < 0.01, n = 3) were significantly higher in the BCP/osteogenic-group MSCs than in the coralline-derived-HA/osteogenic-group MSCs

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