Fig. 2From: Benefits of biphasic calcium phosphate hybrid scaffold-driven osteogenic differentiation of mesenchymal stem cells through upregulated leptin receptor expressionmRNA expression of osteogenic genes and leptin-R. After 7Â days of culture, the mRNA levels of leptin-R (*p < 0.05, n = 3), osteopontin (*p < 0.05, n = 3), and Runx2 (*p < 0.05, n = 3) were significantly higher in the PLGA/BCP-group MSCs than in the PLGA/coralline-derived-HA-group MSCs. After 14Â days of culture, the mRNA levels of leptin-R (**p < 0.01, n = 3), osteopontin (**p < 0.01, n = 3), osteocalcin (*p < 0.05, n = 3), and Runx2 (**p < 0.01, n = 3) were significantly higher in the PLGA/BCP-group MSCs than in the PLGA/coralline-derived-HA-group MSCsBack to article page