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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Benefits of biphasic calcium phosphate hybrid scaffold-driven osteogenic differentiation of mesenchymal stem cells through upregulated leptin receptor expression

Fig. 2

mRNA expression of osteogenic genes and leptin-R. After 7 days of culture, the mRNA levels of leptin-R (*p < 0.05, n = 3), osteopontin (*p < 0.05, n = 3), and Runx2 (*p < 0.05, n = 3) were significantly higher in the PLGA/BCP-group MSCs than in the PLGA/coralline-derived-HA-group MSCs. After 14 days of culture, the mRNA levels of leptin-R (**p < 0.01, n = 3), osteopontin (**p < 0.01, n = 3), osteocalcin (*p < 0.05, n = 3), and Runx2 (**p < 0.01, n = 3) were significantly higher in the PLGA/BCP-group MSCs than in the PLGA/coralline-derived-HA-group MSCs

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