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Table 2 Measurements with peripheral quantitative computed tomography (pQCT)

From: Changes over time in callus formation caused by intermittently administering PTH in rabbit distraction osteogenesis models

 

6 weeks

8 weeks

10 weeks

 

Control

PTH30

P-values

Control

PTH30

P-values

Control

PTH30

P-values

n

5

5

 

5

5

 

5

5

 

Total-Area (mm3)

63 ± 8

70 ± 14

ns

64 ± 22

83 ± 13

P < 0.05

65 ± 12

82 ± 26

P < 0.05

Cortical-Area: 690 mg/cm3 (mm3)

19 ± 4

22 ± 11

ns

25 ± 7

25 ± 8

ns

21 ± 3

21 ± 5

ns

Cortical-Area: 267 mg/cm3 (mm3)

60 ± 7

68 ± 10

P < 0.05

50 ± 14

54 ± 19

ns

35 ± 7

40 ± 6

ns

Medial-Area (mm3)

43 ± 7

50.7 ± 11

ns

29 ± 5

55 ± 8

P < 0.05

39 ± 7

54 ± 18

P < 0.05

Cortical-Peri (mm)

28 ± 2

30 ± 3

ns

28 ± 5

32 ± 2

ns

28 ± 3

32 ± 5

ns

Cortical-Endo (mm)

23 ± 3

24 ± 3

ns

21 ± 7

29 ± 2

P < 0.05

23 ± 4

27 ± 5

P < 0.05

Cortical-Thk (mm)

0.7 ± 0.02

0.8 ± 0.4

ns

1.1 ± 0.4

0.9 ± 0.3

ns

0.9 ± 0.2

0.7 ± 0.2

ns

  1. Total-Area total cross-sectional area of the callus, Cortical-Area cortical bone cross-sectional area (690 mg/cm3: typical cortical bone, 267 mg/cm3: including immature bone cortex), Medial-Area medullary cavity area, Cortical-Peri perimeter of the cortical bone periosteum, Cortical-Endo perimeter of the cortical bone endosteum, Cortical-Thk cortical bone thickness
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X