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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Acceleration of bone-defect repair by using A-W MGC loaded with BMP2 and triple point-mutant HIF1α-expressing BMSCs

Fig. 6

HE staining images (×100) from different groups 12 weeks after surgery. a A-W MGC transplanted with BMSCs that were infected with Adv-HIF1αmu-hrGFP and Adv-BMP2-hrGFP. b A-W MGC transplanted with BMSCs that were infected Adv-BMP2-hrGFP. c Autogenous bone graft group. d A-W MGC transplanted with BMSCs that were infected with Adv-HIF1αmu-hrGFP. e A-W MGC. Arrows: cell nuclei. HE: hematoxylin and eosin. A-W MGC: apatite-wollastonite magnetic bioactive glass-ceramic. BMSCs: mesenchymal stem cells. BMP2: bone morphogenetic protein 2. hrGFP: human renilla reniformis green fluorescent protein. HIF1αmu: hypoxia-inducible factor 1 mutation

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