Fig. 9

Gross appearance and analysis of lesions in goat model at time of implantation and at 3 and 12 months. Appearance of lesions treated with marrow stimulation alone (top left) and marrow stimulation plus implantation of a CVOCA (top right) at time of surgical intervention. Normalized grade scores for repair tissue in lesions treated with marrow stimulation alone at 3 months (a) and 12 months (c) or marrow stimulation plus the CVOCA at 3 months (b) and 12 months (d), along with representative images of repair tissue in lesions from each condition and time point (bottom). The maximum normalized grade score possible is 10. The bar graph shows mean ± SEM