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Figure 3 | Journal of Orthopaedic Surgery and Research

Figure 3

From: Utilization of a genetically modified muscle flap for local BMP-2 production and its effects on bone healing: a histomorphometric and radiological study in a rat model

Figure 3

Radiographic evaluation of bone formation. Animals were positioned prone with the left hind limb externally rotated for x-ray imaging. X-ray images were obtained between the third and thirteenth day after surgery (A) and on the day of euthanasia (14 weeks postoperatively (B)). Here, we present images from an animal of the Ad.BMP-2 group. The images were analyzed assessing radiological density by gray-scale analysis. The region of interest used was defined as the area between the second screw and third screw (distally). An increase of high-density tissue, corresponding to mineralized bone between the first and last x-ray was seen in all three groups (C). The increase was highest in the Ad.BMP-2 group.

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