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Table 1 Study characteristics

From: Does hydroxyapatite coating have no advantage over porous coating in primary total hip arthroplasty? A meta-analysis

Study Study design Sample size (HA/control) Mean ages of patients (years) Sex distribution (female/male) Inclusion criteria
Camazzola et al. [28] RCT 61 (34/27) 48.2 ± 9.0/50.4 ± 8.7 22/39 Men younger than 60 years and women younger than 65 years having elective primary THA
Dorr et al. [16] Retrospective, matched pair 30 (15/15) 55 (38–71) 10/5 Patients who underwent bilateral primary THA
Hamadouche et al. [34] RCT 45 (22/23) 65/64 41/39 Patients with osteoarthritis of the hip requiring THA
Incavo et al. [32] RCT 50 (24/26) 55 NR Patients who underwent THA
Kim et al. [23] RCT 100 (50/50) 45.3 (27–61) 14/36 Patients who underwent sequential bilateral primary THA
Kim et al. [24] RCT 110 (55/55) 46.3 (27–63) 39/16 Patients who underwent bilateral primary THA
Lee and Lee 2007 [33] RCT 40 (20/20) 44 (25–72) 2/18 Patients who had late-stage bilateral osteonecrosis were randomly treated with bilateral THA
Lombardi Jr. et al. [12] Retrospective, observational study 131 (46/85) 52 (29–72)/51 (22–78) 67/97 Patients who underwent THA using a MHP
Mcpherson et al. [36] Retrospective, matched pair 84 (42/42) 55 ± 11.4/56.5 ± 11.7 36/48 Patients of the same gender, bone type, activity level, and diagnosis, ages within 5 years, weight within 25 pounds, Charnley activity class
Parvizi et al. [9] Prospective, matched-pair 86 (43/43) 66.8 ± 6.2/65.7 ± 5.9 NR The patients matched for age, sex, weight, diagnosis, Charnley class, operative approach, bone quality, femoral head size, type of acetabular component, and duration of follow-up
Paulsen et al. [38] Retrospective comparison 3,158/4,749 NR 3,834/4,073 Patients underwent primary uncemented THA, who were younger than 70 years of age at surgery
Ranawat et al. [35] RCT 174 (92/82) 54.9 (29.4–67.5)/55.5 (28.6–71.8) 38/114 Patients received cementless THA with the Ranawat-Burstein metaphyseal-diaphyseal fit hip system
Rothman et al. [10] Retrospective, matched pair 104 (52/52) 64 (31.2–86.1) 49/49 Consecutive THA with use of Taperloc stem, matched for age, sex, weight, diagnosis, Charnley class, operative approach, and duration of follow-up
Sanchez-Sotelo et al. [37] Retrospective, matched-pair 136 (68/68) 54 (23–66)/56 (22–67) 56/80 Patients who had a primary hip replacement with insertion of either a porous-coated or HA-coated Omniflex femoral componene
Sano et al. [39] Retrospective, observational study 55 (24/31) 64.0 (51–83)/62.7 (41–80) 49/3 Patients in whom surgery was performed at least 2 years before the present study
Santori et al. [14] Retrospective, observational study 227 (158/69) NR NR Patients underwent THA with the anatomic prosthesis
Søballe et al. [4] RCT 26 (14/12) 56.8 (48–63)/58.6 (50–68) NR Patients who underwent THR to receive prosthetic with either Ti-alloy coating or HA coating
Tanzer et al. [22] RCT 39 (17/22) 66 (54–80)/64 (43–78) 13/26 Patients undergoing a cementless THA
Tanzer et al. [31] RCT 318 (164/154) 64.5 ± 9.9/63.1 ± 10.5 153/165 All patients who underwent cementless THA
Yee et al. [30] RCT 62 (35/27) 48.2 ± 9.0/50.4 ± 8.7 11/22 Men younger than 60 years of age and women younger than 65 years of age undergoing primary THA
Yoon et al. [29] RCT 75 (37/38) 45.3 (20–69)/46.0 (23–71) 14/49 Patients who underwent THA use a multilock femoral stem with or without HA/TCP coating
  1. RCT randomized controlled trials, HA hydroxyapatite, NR not reported, THA total hip arthroplasty, TCP tricalcium phosphate.