Figure 1

Electron microscopy of HF-hMSC populations during osteogenic culture on titanium discs and screws. HF-hMSC populations were seeded onto either Ti discs (A-E) or Ti screws (F-J) and cultured for up to 28 days in osteogenic medium. Representative images of three fields of view are presented for each time point at days 1, 7, 14, 21 and 28 post-seeding. Note at day 14, the restricted localisation of the cells to the core surface of the screw during expansion of the population.