Figure 4
From: Mesenchymal stem cells overexpressing Ihh promote bone repair
Macroscopic observations further strengthened the idea that Ihh+MSCs/hydroxyapatite complex promote bone regeneration. At 12 weeks after the implantation, complete bone union was observed in group implanted with EGFP+ Ihh+ MSCs/HA constructs (c), while bone defects were persistent in control groups (a and b). Arrows in all panels points to the injury sites. Note that the hydroxyapatite complex was undetectable in any group at this time point.