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Table 1 Histological scores at 24 and 52 weeks after implantation

From: Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells

 

24 weeks (n=3)

52 weeks (n=3)

pvalue

Cell morphology

2.7 (2–3)

2.7 (2–3)

N.S.

Matrix staining (metachromasia)

1.7 (1–2)

1.7 (1–2)

N.S.

Surface regularity

3

3

N.S.

Thickness of cartilage

1.3 (1–2)

1.7 (1–2)

N.S.

Integration of donor to adjacent host cartilage

1.3 (1–2)

0.7 (0–1)

N.S.

Total score (score range 0–14)

10 (8–11)

9.7 (9–10)

N.S.

  1. N.S. not significant.