From: Serum levels of M-CSF, RANKL and OPG in rats fed with Kashin-Beck disease-affected diet
Item | Time (weeks) | A | B | C | D | E |
---|---|---|---|---|---|---|
MCSF (pg/ml) | 4 | 234.08 ± 82.08 | 116.61 ± 92.67 | 151.27 ± 81.22 | 246.76 ± 97.41 | 411.85 ± 123.73 |
8 | 231.36 ± 85.53* | 138.82 ± 95.76* | 376.30 ± 128.19* | 259.64 ± 88.97* | 589.62 ± 147.85** | |
12 | 232.56 ± 88.13 | 228.27 ± 76.63 | 250.77 ± 95.40 | 248.09 ± 93.52 | 258.87 ± 89.86 | |
RANKL (ng/ml) | 4 | 0.034 ± 0.025# | 0.079 ± 0.038# | 0.138 ± 0.059# | 0.068 ± 0.017# | 0.228 ± 0.085## |
8 | 0.041 ± 0.017 | 0.084 ± 0.041 | 0.178 ± 0.022 | 0.052 ± 0.028 | 0.160 ± 0.059 | |
12 | 0.058 ± 0.013 | 0.072 ± 0.038 | 0.153 ± 0.027 | 0.053 ± 0.011 | 0.105 ± 0.042 | |
OPG (ng/ml) | 4 | 1.415 ± 0.312※ | 1.492 ± 0.391※ | 1.734 ± 0.778※ | 1.324 ± 0.773※ | 2.688 ± 0.615※※ |
8 | 1.665 ± 0.597 | 1.542 ± 0.363 | 1.376 ± 0.369 | 1.486 ± 0.598 | 1.359 ± 0.517 | |
12 | 1.672 ± 0.476 | 1.403 ± 0.624 | 1.241 ± 0.134 | 1.461 ± 0.708 | 1.288 ± 0.612 |