Figure 3

Gene expression analysis of AF cells cultured in 3D scaffolds. Gene expression analysis of AF cells in empty PGA-PLGA-PVDF scaffolds (3D), scaffolds loaded with TGF-beta 1 (3D TGF), or TGF-beta 1-hyaluronan (3D TGF HA) was performed after 7 and 21 days of tissue culture. Fold changes of genes coding extracellular matrix molecules and matrix modifying enzymes are given compared to their expression level found in AF cells cultured in empty scaffolds at day 7 or day 21. Bars show the mean of each triplicate and standard deviation. Asterisks (*) indicate significant differential expression (p < 0.05).