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Table 2 Pooled odds ratio for operative fixation versus conservative treatment in the meta-analysis

From: Avascular necrosis in proximal humeral fractures in patients treated with operative fixation: a meta-analysis

Subgroups

Sample size

Number of studies

Random model

Test of heterogeneity

Egger's test for publication bias

Case

Control

OR (95% CI)

Z

p value

Q

p value

I2(%)

t

p value

Overall effects

142

149

7

1.42 (0.33–6.11)

0.47

0.64

16.68

0.01

64

1.52

0.19

Study design

           

  Retrospective

109

78

4

0.73 (0.15–3.55)

1.21

0.23

6.89

0.08

56

0.99

0.43

  Prospective

26

27

2

1.03 (0.17–6.40)

0.03

0.98

0.92

0.34

0.0

-0.03

0.98

Sample size

           

  Sample size ≤40

66

81

5

1.36 (0.48–3.86)

0.60

0.55

1.86

0.76

0.0

0.30

0.79

  Sample size >40

102

87

3

1.52 (0.10–24.11)

0.29

0.77

14.35

0.001

86.1

-

-

Ethnicity

           

  European

122

134

6

1.60 (0.30–8.51)

0.55

0.58

16.64

0.005

70

1.62

0.18

  Asian

20

15

1

0.74 (0.04–12.82)

0.21

0.83

-

-

-

-

-

Operative approaches

           

  Plate fixation

89

39

2

0.20 (0.05–0.76)

2.35

0.019

1.01

0.315

0.8

-

-

  Tension band wiring fixation

27

26

2

1.77 (0.41–7.70)

0.76

0.445

0.20

0.657

0.0

-

-

  Others

26

84

3

4.01 (0.31–45.26)

1.07

0.285

5.68

0.058

64.8

0.03

0.983