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Table 4 Comparison of metal ion levels and clinical outcomes in various large-head MOM THA systems

From: Does bearing size influence metal ion levels in large-head metal-on-metal total hip arthroplasty? A comparison of three total hip systems

Authors Study design Metal ion levels Clinical outcomes
Lavigne et al. [20] Comparison of metal ion levels in four different large-head MOM THA systems (Biomet modular M2a-Magnum system, Depuy ASR XL system, Smith and Nephew Birmingham socket system and Zimmer Durom LDH system) For chromium ion levels, no significant differences between four groups. For cobalt ion levels, a significant difference between the groups at 3, 6, 12 and 24 months, with the Zimmer implant showing the highest levels and the Biomet implant the lowest (p = 0.027, <0.001, 0.007 and 0.001 at 3, 6, 12 and 24 months, respectively) Not evaluated
Lardanchet et al. [37] Comparison of metal ion levels in three different large-head MOM THA systems (Biomet modular M2a-Magnum system, Zimmer Durom LDH system and Wright Conserve Total system) Cobalt ion levels significantly higher with Conserve Total than with Durom and M2a Magnum (no significant difference between the last two). Chromium ion levels significantly lower with Durom than with Conserve Total. No significant differences for chromium levels between Durom and M2a Magnum or between Conserve Total and M2a Magnum Better outcome scores in M2a Magnum as compared to Conserve Total (p = 0.008, Wilcoxon test) with no significant difference between Durom and M2a Magnum (p = 0.22) or between Durom and Conserve Total (p = 0.11)
Current study Comparison of metal ion levels in three different large-head MOM THA systems (Two monoblock systems, Zimmer Durom LDH system and Smith and Nephew Birmingham socket system; one modular system, Depuy Pinnacle socket system) Metal ions significantly higher in the two monoblock head systems (Zimmer Durom LDH system, and Smith and Nephew Birmingham socket system) as compared to the modular Pinnacle socket system from Depuy No significant difference in all three systems