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Table 3 Effect of femoral head size on metal ion concentrations

From: Does bearing size influence metal ion levels in large-head metal-on-metal total hip arthroplasty? A comparison of three total hip systems

Authors Year Study design Follow-up Metal ion levels (μg/l) p value Conclusion
Antoniou et al. [32] 2008 Comparison of 36 mm head MOM THA with 28 mm head MOM THA 12 months Large head, Cr 0.4, Co 2.3 >0.2 for Cr No difference in metal ion levels in small or large-head MOM THA
Small head, Cr 0.6, Co 2.6 >0.15 for Co
Daniel et al. [31] 2008 Comparison of large-head MOM THA (42 to 54) with 28 mm head MOM THA 12 months Large head, Cr 1.4, Co 2.3 Not significant No difference in metal ion levels in small or large-head MOM THA
Small head, Cr 1.7, Co 1.7
Bernstein et al. [34] 2011 Comparison of large-head MOM THA (40 to 44) with small-head MOM (28 and 36 mm) THA 12 months Large head, Cr 0.51, Co 2.22 0.29 for Cr No difference in metal ion levels in small or large-head MOM THA
Small head, Cr 0.78, Co 2.34 0.42 for Co
Hallows et al. [35] 2011 Comparison of large-head MOM THA (38 and larger) with small-head MOM (28 and 32 mm) THA 12 months Large head, Cr 0.8, Co 0.7 0.0158 for Cr Chromium ion levels in blood higher for small-head MOM THA as compared to large-head MOM THA. No difference in blood Cobalt ion levels
Small head, Cr 2.1, Co 0.7 0.869 for Co
  1. Studies comparing small-head MOM THA with large-head MOM THA.