Does bearing size influence metal ion levels in large-head metal-on-metal total hip arthroplasty? A comparison of three total hip systems

Smith, James; Lee, David; Bali, Kamal; Railton, Pam; Kinniburgh, David; Faris, Peter; Marshall, Deborah; Burkart, Brian; Powell, James

doi:10.1186/1749-799X-9-3

Journal of Orthopaedic Surgery and Research

Table 2 Effect of femoral head size on metal ion concentrations

From: Does bearing size influence metal ion levels in large-head metal-on-metal total hip arthroplasty? A comparison of three total hip systems

Authors	Year	Study design	Follow-up	Metal ion levels (μg/l)	p value	Conclusion
Clarke et al. [29]	2003	Comparison of large-head MOM resurfacing (38 to 54) with 28 mm head MOM THA	16 months	Large head, Cr 53, Co 38	0.0001 for Cr	Metal ion levels higher for larger diameter bearings
Clarke et al. [29]	2003		16 months	Small head: Cr 29, Co 22 (all values nmol/l)	0.0021 for Co	Metal ion levels higher for larger diameter bearings
Daniel et al. [30]	2006	Comparison of large-head MOM resurfacing (50 to 54) with 28 mm head MOM THA	12 months	Large head, Cr 1.3, Co 2.4	0.055 for Cr	No difference in metal ion levels in small or large-head MOM bearings
Daniel et al. [30]	2006		12 months	Small head, Cr 1.7, Co 1.7	0.28 for Co
Langton et al. [28]	2008	Comparison of large-head MOM resurfacing (≥53 mm) with small-head MOM resurfacing (≤53 mm)	26 months	Large head, Cr 3.04, Co 1.48	0.004 for Cr	Metal ion levels higher for smaller diameter MOM resurfacings
Langton et al. [28]	2008		26 months	Small head, Cr 4.12, Co 2.43	0.007 for Co
Vendittoli et al. [33]	2010	Comparison of large-head MOM resurfacing (40 to 58) with 28 mm head MOM THA	24 months	Large head, Cr 1.58, Co 0.67	0.819 for Cr	No difference in metal ion levels in small or large-head MOM bearings
Vendittoli et al. [33]	2010		24 months	Small head, Cr 1.62, Co 0.94	0.207 for Co
Pattyn et al. [36]	2011	Comparison of large-head MOM resurfacing (Durom and BHR) with 28 mm head MOM THA	24 months	Large-head Durom, Cr 1.07, Co 0.79	Significant only in Co levels (Durom vs small head MOM THA)	Metal ions lower in larger head Durom resurfacing as compared to small-head MOM THA. No difference between BHR and small-head MOM THA
				Large-head BHR, Cr 1.54, Co 1.86
				Small head, Cr 1.25, Co 1.79
Moroni et al. [42]	2008	Comparison of large head MOM resurfacing (average diameter 48) with 28 mm head MOM THA	24 months	Large head, Cr 2.3, Co 1.4	0.06 for Cr	No difference in metal ion levels in small or large-head MOM bearings
Moroni et al. [42]	2008		24 months	Small head, Cr 1.73, Co 1.33	0.30 for Co

Studies evaluating MOM hip resurfacing alone or comparing MOM resurfacing with small-head MOM THA.

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ISSN: 1749-799X

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