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Table 2 Effect of femoral head size on metal ion concentrations

From: Does bearing size influence metal ion levels in large-head metal-on-metal total hip arthroplasty? A comparison of three total hip systems

Authors Year Study design Follow-up Metal ion levels (μg/l) p value Conclusion
Clarke et al. [29] 2003 Comparison of large-head MOM resurfacing (38 to 54) with 28 mm head MOM THA 16 months Large head, Cr 53, Co 38 0.0001 for Cr Metal ion levels higher for larger diameter bearings
Small head: Cr 29, Co 22 (all values nmol/l) 0.0021 for Co
Daniel et al. [30] 2006 Comparison of large-head MOM resurfacing (50 to 54) with 28 mm head MOM THA 12 months Large head, Cr 1.3, Co 2.4 0.055 for Cr No difference in metal ion levels in small or large-head MOM bearings
Small head, Cr 1.7, Co 1.7 0.28 for Co
Langton et al. [28] 2008 Comparison of large-head MOM resurfacing (≥53 mm) with small-head MOM resurfacing (≤53 mm) 26 months Large head, Cr 3.04, Co 1.48 0.004 for Cr Metal ion levels higher for smaller diameter MOM resurfacings
Small head, Cr 4.12, Co 2.43 0.007 for Co
Vendittoli et al. [33] 2010 Comparison of large-head MOM resurfacing (40 to 58) with 28 mm head MOM THA 24 months Large head, Cr 1.58, Co 0.67 0.819 for Cr No difference in metal ion levels in small or large-head MOM bearings
Small head, Cr 1.62, Co 0.94 0.207 for Co
Pattyn et al. [36] 2011 Comparison of large-head MOM resurfacing (Durom and BHR) with 28 mm head MOM THA 24 months Large-head Durom, Cr 1.07, Co 0.79 Significant only in Co levels (Durom vs small head MOM THA) Metal ions lower in larger head Durom resurfacing as compared to small-head MOM THA. No difference between BHR and small-head MOM THA
Large-head BHR, Cr 1.54, Co 1.86
Small head, Cr 1.25, Co 1.79
Moroni et al. [42] 2008 Comparison of large head MOM resurfacing (average diameter 48) with 28 mm head MOM THA 24 months Large head, Cr 2.3, Co 1.4 0.06 for Cr No difference in metal ion levels in small or large-head MOM bearings
Small head, Cr 1.73, Co 1.33 0.30 for Co
  1. Studies evaluating MOM hip resurfacing alone or comparing MOM resurfacing with small-head MOM THA.