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Table 4 Sensitivity, Specificity and Predictive values of PCT at 0.5 and 0.4 ng/ml

From: Serum Procalcitonin is a sensitive and specific marker in the diagnosis of septic arthritis and acute osteomyelitis

Groups

PCT (ng/ml)

Sensitivity % 95% CI

Specificity % 95% CI

PPV % 95% CI

NPV % 95% CI

LR

Confirmed Pyogenic vs presumed + Non – pyogenic

0.5

66.7 (46 – 83.4)

91 (80 – 97)

78.2 (56 – 92.5

84.7 (73–92.5)

7.33

0.4

85.2 (66.3 – 95.8)

87.3 (75.5 – 94.7)

76.6 (57.7 –90.1)

92.3 (81.5 - 98)

6.69

Confirmed+ Presumed vs non – pyogenic

0.5

47.9 (33.2 – 62.8)

100 (89.7 – 100)

100 (85.2 -100)

57.6 (44.1 -70.4)

*

0.4

62.5 (47.4 – 76)

100 (89.7 – 100)

100 (88.4 – 100)

65.4 (60 – 78)

*

Confirmed vs non – pyogenic

0.5

66.67 (46 – 83.4)

100 (91.2 - 100)

100 (87.4 – 100)

86.3 (77.8 – 94.9)

*

0.4

85.19 (66.3 – 95.8)

100 (90.2 – 100)

100 (88.7 – 100)

93.8 (82.7 - 96.5)

*

  1. PCT Procalcitonin, PPV Positive Predictive Value, NPV Negative Predictive Value, CI Confidence Interval, LR Likelihood Ratio, * LR cannot be calculated because of zero value.