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Table 1 Urinary calcium excretion (mmol/L) in different treatment groups over time

From: Alendronate (ALN) combined with Osteoprotegerin (OPG) significantly improves mechanical properties of long bone than the single use of ALN or OPG in the ovariectomized rats

Treatment Groups 12 wks after OVX (before treatment) 24 wks after OVX (12 wks after treatment)
Sham 1.61 ± 0.30 1.81 ± 0.45
OVX 1.69 ± 0.25 2.11 ± 0.39 a
OVX+ALN 1.67 ± 0.30 1.89 ± 0.33
OVX+OPG-Fc 1.56 ± 0.31 1.43 ± 0.35 b
OVX+ALN+OPG-Fc 1.51 ± 0.40 1.48 ± 0.45 b
  1. (a): Group had higher value than that of all other groups at the given time, p < 0.05.
  2. (b): Group had significantly lower value than that of Sham, OVX and OVX+ALN groups, p < 0.05