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Table 1 Summary of study Characteristics

From: Is surgical intervention more effective than non-surgical treatment for carpal tunnel syndrome? a systematic review

ID Authors Year Country Design Sample size Inclusion and exclusion criteria Study Quality (Jadad et al. Scores; SEQES)
1 Jarvik et al. [13] 2009 USA RCT 116
57( OCTR or ECTR)
59( Multi-modality* )
1. Clinical diagnosis of CTS greater than 2 weeks
2. Confirmed by electrodiagnostic studies
3. In absence of electrodiagnostic criteria, positive in night pain and flick test
4. Excluded if previous treatment with CTS release surgery, severe thenar muscle atrophy
3/5
39/48
2 Elwakil et al. [14] 2007 Egypt Comparative cohort study 60
30 (OCTR)
30 ( Laser )
Clinical diagnosis of CTS 1/5
29/48
3 Ucan et al. [15] 2006 Turkey RCT 57
11( OCTR)
23 ( Splinting )
23 ( Splinting + one dose steroid injection)
1. Mild to moderate clinical diagnosis of CTS greater than 6 months
2. Confirmed by electrodiagnostic studies
3. Excluded if advanced CTS, thenar atrophy or previous CTS treatment
2/5
36/48
4 Ly-Pen et al [16]. 2005 Spain RCT 163
80( OCTR)
83 (one or two-dose steroid injection )
1. Clinical diagnosis of CTS greater than 3 months
2. Confirmed by electrodiagnostic studies
3. Excluded if previous treatment with CTS release surgery, severe thenar muscle atrophy
3/5
35/48
5 Hui et al. [17] 2005 Hong Kong RCT 50
25( OCTR)
25 ( One dose steroid injection )
1. Clinical diagnosis of CTS greater than
3 months but less than 1 year
2. Confirmed by electrodiagnostic studies
3. Excluded if severe thenar muscle atrophy, ulnar, radial neuropathy
3/5
38/48
6 Demirci et al. [18] 2002 Turkey Comparative cohort study 90
44( OCTR)
46 ( Two-dose steroid injection )
1. Clinical diagnosis of CTS greater than 6 months
2. Confirmed by electrodiagnostic studies
3. Excluded if previous steroid injection, OCTR or distal radius fracture
0/5
31/48
7 Gerritsen et al [19] 2002 Netherlands RCT 176
87( OCTR)
89 ( Splinting )
1. Clinical diagnosis of CTS
2. Confirmed by electrodiagnostic studies
3. Excluded if severe thenar muscle atrophy
3/5 40/48
  1. RCT: randomized clinical trials
  2. OCTR: standard open carpal tunnel release
  3. ECTR: Endoscopic carpal tunnel release