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Table 2 Modified Histological Grading Scale for Defects in Articular Cartilage 3

From: Augmentation of osteochondral repair with hyperbaric oxygenation: a rabbit study

Category Score (points)
1. Filling of defect relative to surface of normal adjacent cartilage  
   > 90% 0
   75-90% 1
   50-74% 2
   25-29% 3
   < 25% 4
2. Cellular morphology (percentage of chondrocytes)  
   > 90% 0
   75-90% 1
   50-74% 2
   25-49% 3
   Mostly fibroblast-like cells 4
3. Surface architecture  
   Normal 0
   Slightly irregular 1
   Fibrillation 2
   Disrupted 3
4. Matrix staining with Safranin O  
   Normal 0
   Slightly reduced 1
   Moderately reduced 2
   Substantially reduced 3
   None 4
5. Tidemark formation  
   > 90% 0
   75-90% 1
   50-74% 2
   25-49% 3
   < 25% 4
6. Integration of repair tissue with adjacent articular cartilage  
   Normal 0
   Decreased cellularity 1
   Small gap 2
   Discontinuity 3
7. Percentage of new subchondral bone  
   > 90% 0
   75-90% 1
   50-79% 2
   25-49% 3
   < 25% 4