Skip to main content
Figure 6 | Journal of Orthopaedic Surgery and Research

Figure 6

From: Role of the VEGF-Flt-1-FAK pathway in the pathogenesis of osteoclastic bone destruction of giant cell tumors of bone

Figure 6

Correlation between pY-Flt-1 and pY-FAK expression and the clinical stage of GCTs at presentation. To determine the status of pY-Flt-1 and pY-FAK in GCT samples, the staining intensity of each specimen was scored as follows: 1 (weak staining; less than 10% of the cells were positive cells), 2 (intermediate staining; 10-50% positive) and 3 (strong staining; >50% positive). The Mann-Whitney U test was used to test the significance of the difference between stages I-II and stage III GCTs. The expression of pY-Flt-1 (a) and pY-FAK (b) in stage III GCTs was significantly higher than the expression levels in stages I-II GCTs (p < 0.05). *; p < 0.05 stages I-II versus stage III).

Back to article page