Figure 4

Pasteurized bone with (MC+; FGF2-) at 4 weeks after grafting shows the grafted bone (left part) and the host bone (right part). Bone formation at the end of the host bone is rather mature (A, B) with osteoclasts on the surface of the bone trabeculae (C, D). Grafted bone characterized by empty lacunae is absorbed and replaced by fibrous tissue (E) associated with osteoclasts on the surface of the pasteurized bone (F). (Original magnification, H&E staining; A; ×70, B; E; ×150, TRAP staining; C; ×70, D; F; ×150).