Figure 1
From: Th1 type lymphocyte reactivity to metals in patients with total hip arthroplasty
Human PBMC/lymphocyte proliferation responses to various concentrations of soluble metal challenge are indicated. Only Nickel indicated significant increases (p < 0.05, t-test) at concentrations of 0.5 and 10 mM. The ranking of the most toxic/inhibitory metals was determined by the lowest concentration of metal required to produce a >50% decrease in the proliferation rate when compared to controls (i.e. <0.5 Proliferation Index). Note: * = p < 0.05, t-test.