Figure 3From: Effect of combined treatment with alendronate and calcitriol on femoral neck strength in osteopenic ratsTotal BMC and BMD at the femoral neck measured by pQCT densitometry. Effects of alendronate (ALN), calcitriol (VitD), and combined alendronate and calcitriol treatments (ALN+VitD) on the pQCT densitometric parameters of total BMC and BMD at the femoral neck in OVX rats after 12 weeks of treatment are shown. The data are presented as mean ± SD (n = 6 per group). # P < 0.05, ### P < 0.001 as compared with corresponding values in saline-treated OVX (unpaired t-test). * P < 0.05, ** P < 0.01 as compared with corresponding values in saline-treated OVX (Tukey's multiple comparison test). Total BMC and BMD were significantly lower in the saline-treated OVX compared with the sham group. Alendronate treatment, with or without calcitriol, induced a significant improvement in both total BMC and BMD.Back to article page