Deletion of vWF A2 domain from MATN1 alters its oligomerization. A. Schematic diagram of Construct 1: MATN1; and Construct 2: MATN1ΔA2. B. Western blot analysis of the conditioned medium from Cos cells transfected with Construct 1 or Construct 2, under the same experimental conditions as described in the Figure 3 legend. Reducing conditions and the molecular weights of the Matn1 oligomers were indicated on the left, while the molecular weights of the Matn1ΔA2 oligomers are indicated on the right.