Figure 4

(A) Undecalcified static image (2×) of distal host (H)/graft (G) junction in the LAP treatment group illustrating perforations in the cranial and caudal cortices that have filled to varying degrees with new appositional bone. Cranially (Cr) in (A), the perforation is almost entirely filled with new bone and extends the entire length of the conduit. (B) Dynamic histomorphometric whole specimen composite of (A) (2×) illustrating extensive uptake of both calcein and tetracycline Fluorochrome labels that extend the length of the 10 mm conduits in the cranial and caudal cortices.