Table 1 Peselected exclusion and inclusion criteria.

Age < 18 years

Written informed consent

Tscherne G3 or Gustilo Typ IIIB/C injuries

Tscherne G0/G1/G2 or Gustilo I°/II°/IIIa° injuries

Multiple life-threatening injuries (polytrauma)

Age > 18 years

Traumatic brain injury

No previous inury of the fracture site

Additional fractures of the ipsi- and/or contralateral extremity

Mono- injury

Manifested compartment syndrome

Surgical treatment within the first 24 h

Blood coagulation disorders

Anticoagulative medication